WHAT IS FLORMIDAL? Flormidal is used to produce sleepiness or drowsiness and to relieve anxiety before surgery or certain procedures. Flormidal is also given to produce amnesia (loss of memory) so that the patient will not remember any discomfort or undesirable effects that may occur after a surgery or procedure. It is also used to produce loss of consciousness before and during surgery. Flormidal is sometimes used in patients in hospital intensive care units to cause unconsciousness. This may allow the patient to withstand the stress of being in the intensive care unit and help the patient cooperate when a machine must be used to assist with breathing. Flormidal is given only by or under the immediate supervision of a doctor trained to use Flormidal. If you will be receiving Flormidal during surgery, your doctor or anesthesiologist will give you the medicine and closely follow your progress. Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in the product labeling, Flormidal is used in certain patients with the following medical condition: Epilepsy HOW SHOULD I USE FLORMIDAL? Use Flormidal as directed by your doctor. Check the label on the medicine for exact dosing instructions. Flormidal is intended for a single use only. You should not use Flormidal for long-term use. Flormidal is usually administered at your doctor's office, hospital, or clinic. If you are using Flormidal at home, carefully follow the directions provided by your doctor or other health care provider. Avoid eating grapefruit or drinking grapefruit juice while you are taking Flormidal. If you miss a dose of Flormidal, contact your doctor immediately. Ask your health care provider any questions you may have about how to use Flormidal. FLORMIDAL DESCRIPTION Flormidal also contains Flormidal 1 mg, benzyl alcohol 1% v/v as preservative and water for injection. Flormidal is a short-acting, water soluble benzodiazepine used as a sedative and anesthetic agent. Because of its water solubility, it is well tolerated locally at the sites of IV or IM injection. Another notable feature of Flormidal is the good cardiovascular stability associated with its use. Flormidal is an imidazobendiazepine. It is 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4) benzodiazepine. The empirical formula of Flormidal is C18H13CIFN3 and its molecular weight is 325.8. FLORMIDAL DOSAGE Tablet: Treatment should be as short as possible. Generally, the duration of treatment varies from a few days to a maximum of 2 weeks. The tapering off process should be tailored to the individual. In certain cases, extension beyond the maximum treatment period may be necessary; if so, it should not take place without re-evaluation of the patient's status. Flormidal should be taken just before going to bed, and swallowed whole with fluid. Standard Dosage: Adults: Dosage Range: 7.5-15 mg. Elderly and Debilitated Patients: Recommended Dose: 7.5 mg. Treatment should be started with the lowest recommended dose. The maximum dose should not be exceeded because of the increased risk of unacceptable CNS adverse effects. Special Dosage Instructions: Patients with Impaired Liver Function: Recommended Dose: 7.5 mg. Flormidal can be taken at any time of the day, provided the patient is subsequently assured of at least 7-8 hrs undisturbed sleep. FLORMIDAL CONTRAINDICATIONS Injectable Flormidal is contraindicated in patients with a known hypersensitivity to the drug. Benzodiazepines are contraindicated in patients with acute narrow-angle glaucoma. Benzodiazepines may be used in patients with open-angle glaucoma only if they are receiving appropriate therapy. Measurements of intraocular pressure in patients without eye disease show a moderate lowering following induction with Flormidal; patients with glaucoma have not been studied. Flormidal Injection is not intended for intrathecal or epidural administration due to the presence of the preservative benzyl alcohol in the dosage form.
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